Hey Chris I've been meaning to write a few reviews when I have time and since your post has been a recent victim of the pointless posts just to follow the rules I thought I'd start here.
I'm including a screen shot so you know what I'm talking about...
First of all I like the overall look of the site, but the home page lacks any hierarchy. It seems like all 4 sections have roughly the same priority. Personally I would recommend that area #2 takes up the entire top part of the page. Quick links to your work (#3) is nice, but currently it doesn't have any context so users may not even understand they're links, let alone what they really are. I think you have enough pull with a featured project and you can even take the chance to provide some explanation around the featured project.
When I look at #2 its not readily obvious that the image and callout are actually supposed to be attached to the paragraph below it. I like the black background and I would actually extend that black area behind the image and quote as well. This would provide instant focus (see my point above) and would visually combine the content into one block. However, you do need to make sure you give that black background some more padding since the text inside is really crowded.
Next, While your global nav is visible it seems much to plain and unimportant. Most all of your body links are a color with an underline yet your main nav is just white. I would highly recommend giving those some visual weight. Tabs the same color as your body links with white text come to mind as the easy solution, but there are many other possibilities.
Finally your portfolio page really needs some love. I know that section is in process so here are a few things that your missing. 1: You need a description of your projects (at the very least a title) so that people know what they're getting by clicking a button. Also as a person who frequently looks at portfolios before hiring freelancers, I would like to know a lot more about the projects, especially your role and if you were part of a team. 2: your portfolio needs a player object instead of linking to animations. I'm pretty sure you have the ability to build a flash container for your animations so don't let me see your work scaled to fit my browser window.
As a final note I really like the use of sIFR for the text shadows. Best of luck.
If at first you don't succeed F1... If that doesn't work try Google!
//// Designer, Developer & Teacher - Interactive, Motion and 3D \\\\
Portfolio at WhenImNotSleeping.com